Author: Jonathan McLatchie

^{Type
post

Author
Jonathan McLatchie

Date
February 6, 2026

Categories
Evolution
Intelligent Design
Tagged
, Center for Science and Culture, Chlamydomonas reinhardtii, citrate, Creation Myths, Daniel Stern Cardinale, Darwin Devolves, Discovery Institute, DNA, DNA replication, DNA replisome, Escherichia coli, evolution, generation turnover time, genome duplication, intelligent design, Irreducible Complexity, irreducibly complex systems, lizards, Michael Behe, multicellularity, mutation rates, mutations, natural selection, neutral mutations, Paramecium tetraurelia, placenta, population size, retrovirus, Richard Lenski, Rutgers University, Scott Minnich, tetherin, tetherin antagonism, type III secretion system, viruses, YouTube channels}

Irreducible Complexity: A Reply and Challenge to Daniel Stern Cardinale

_{Jonathan McLatchie
February 6, 2026

Evolution, Intelligent Design

14}

I invite Stern Cardinale to attempt to provide a plausible evolutionary explanation of the origins of a complex system such as DNA replication. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
January 28, 2026

Categories
Evolution
Genetics
Intelligent Design
Tagged
, Africa, African sleeping sickness, APOL1, Daniel Melamed, diseases, engineering, genes, genetic mutations, genomes, germline genome, haploid, heterozygotes, HindIII, homozygotes, Israel, malaria, MEMDS, mutation DNA, Mutation Enrichment followed by Maximum Depth Sequencing, mutation frequency, mutations, Proceedings of the National Academy of Sciences, randomness, restriction enzyme, sperm, sperm DNA, Trypanosoma brucei, University of Haifa, wild-type DNA}

Could Genetic Mutations Be Non-Random? New Evidence for Mutational Bias

_{Jonathan McLatchie
January 28, 2026

Evolution, Genetics, Intelligent Design

4}

The researchers examined the emergence of a mutation in the human APOL1 gene that confers protection from African sleeping sickness. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
January 14, 2026

Categories
Fine-tuning
Intelligent Design
Physics
Tagged
, Bayesian inference, Bayesian reasoning, causal ramification, chance, cosmic design, fine-tuning, fine-tuning arguments, improbability, intelligent design, Journal for General Philosophy of Science, King’s College London, multiverse, observation biases, philosophy, physical laws, physicists, physics, probability, Roberto Fumagalli, theism, universe}

New Peer-Reviewed Paper Defends Cosmic Fine-Tuning Argument

_{Jonathan McLatchie
January 14, 2026

Fine-tuning, Intelligent Design, Physics

11}

Fumagalli does not in the end state whether he himself lands on the multiverse hypothesis, cosmic design, or unknown physics as the best explanation. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
January 5, 2026

Categories
Earth Sciences
Origin of Life
Planetology
Tagged
, AlphaFold, atmosphere, biochemistry, biological complexity, chance, disorder, entropy, Francis Crick, Imperial College London, informational content, intelligence, intelligent design, Last Universal Common Ancestor, Leslie Orgel, LUCA, molecular assembly, origin of life, panspermia, physical biasing, primitive earth, protocell, Robert E. Endres, universe, water, zircon}

New Paper Argues for the “Unreasonable Likelihood of Being”

_{Jonathan McLatchie
January 5, 2026

Earth Sciences, Origin of Life, Planetology

5}

How long did life have to get started? Endres notes that life on earth could not have emerged until after two early global sterilizing impacts. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
September 16, 2025

Categories
Evolution
Intelligent Design
Tagged
, cellular life, cofactors, David A. Hullender, DNA repair, elementary particles, Elsevier, Elsevier journals, enzymes, evolution, Fred Hoyle, intelligent design, Jerry Coyne, Mycoplasma genitalium, Mycoplasma mycoides, naturalistic evolutionary processes, Olen R. Brown, oxidative phosphorylation, Progress in Biophysics and Molecular Biology, universe, University of Missouri, University of Texas at Arlington, Why Evolution Is True}

To a Pro-Intelligent Design Paper, Biologist Jerry Coyne Reacts with Question-Begging

_{Jonathan McLatchie
September 16, 2025

Evolution, Intelligent Design

6}

The paper seeks to elucidate the plausibility of naturalistic evolutionary processes generating a minimal living cell. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
July 30, 2025

Categories
Biology
Evolution
Intelligent Design
Tagged
, amino acids, Arginine, biosynthesis, blind processes, design logic, DNA, engineering, enzymes, evolution, genes, histidine, homology, intelligent design, mRNA, operons, prokaryotes, recurring design logic, regulation, Ribosome, RNA polymerase, transcription, translation, tryptophan, unguided processes}

Recurring Design Logic in Attenuation Mechanisms

_{Jonathan McLatchie
July 30, 2025

Biology, Evolution, Intelligent Design

4}

Despite the striking parallels between these systems in terms of the design logic, these attenuation systems are not evolutionarily related to one another. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
July 29, 2025

Categories
Biology
Evolution
Intelligent Design
Tagged
, Arginine, bacteria, bacterial cell, biosynthesis, DNA, enzymes, genes, lactose, operons, recurring design logic, regulatory systems, RNA polymerase, structural motif, transcriptional hierarchies, tryptophan}

Recurring Design Logic in Operon Regulation

_{Jonathan McLatchie
July 29, 2025

Biology, Evolution, Intelligent Design

3}

As we see in these two examples, the design logic is the same. And yet, these two systems are not evolutionarily related to one another. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
July 17, 2025

Categories
Biology
Evolution
Intelligent Design
Science Reporting
Tagged
, assembly, bacteria, evolution, fact check, flagellum, headlines, Imperial College London, intelligent design, mathematical plausibility, microbiology, propellers, proteins, swimming, undirected processes}

Fact Check: Has a Study Shown “How Bacteria Evolved Powered-Up Propellers”?

_{Jonathan McLatchie
July 17, 2025

Biology, Evolution, Intelligent Design, Science Reporting

6}

This is a classic case of the media overstating the evidence for some evolutionary claim. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
June 18, 2025

Categories
Biology
Evolution
Intelligent Design
Tagged
, alternative splicing, amino acids, animation, complexity, development, DNA, eukaryotes, evolution, exons, Francis Crick, genes, intelligent causation, intelligent design, introns, junk DNA, MicroRNAs, mRNA, proteins, Ribosome, spliceosome, splicing}

Evolutionary Obstacles to the Origin of Introns

_{Jonathan McLatchie
June 18, 2025

Biology, Evolution, Intelligent Design

18}

The only type of explanation that adequately accounts for this type of phenomenon is a goal-directed, or intelligent, cause. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
May 26, 2025

Categories
Evolution
Intelligent Design
Medicine
Tagged
, anaphase, biology, cancer, cells, chromatids, chromosome, DNA, eukaryotic cell cycle, intelligent cause, intelligent design, Irreducible Complexity, kinetochore, mitotic cell division, mitotic spindle, oocytes, spindle assembly checkpoint, tumors}

How Do Mitotic Errors Affect Cell Proliferation?

_{Jonathan McLatchie
May 26, 2025

Evolution, Intelligent Design, Medicine

12}

This review furthers the argument that I have developed elsewhere that the eukaryotic cell division cycle is elegantly engineered and irreducibly complex. Read More ›