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anaphase

Mitosiscycle
Photo credit: Animalculist, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons.

How Do Mitotic Errors Affect Cell Proliferation?

This review furthers the argument that I have developed elsewhere that the eukaryotic cell division cycle is elegantly engineered and irreducibly complex. Read More ›
African_clawed_frogs;_Xenopus_laevis
Photo: Clawed frogs, by Muffet, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons.

Irreducible Complexity Nested Within Irreducible Complexity: The Case of Chromosome Condensation

It is highly implausible that such a wonder of engineering arose by means of an unguided evolutionary process. Read More ›
Cell_division.tif
Image: Cell division, via Wikimedia Commons.

The Eukaryotic Cell Cycle: An Irreducibly Complex System

Any system that achieves a complex higher-level objective by means of various well-matched interacting components requires foresight to come about. Read More ›
The_anaphase_process_in_root_cells
Photo: Anaphase, root cells, by Radosław.pyt, CC BY 4.0 <https://creativecommons.org/licenses/by/4.0>, via Wikimedia Commons.

Engineered Elegance: Generating the Wait Anaphase Signal

Even a single unattached kinetochore is sufficient to trigger the wait anaphase signal, which inhibits activation of the APC/C that drives entry into anaphase. Read More ›
Mitosis_cycle
Photo credit: Animalculist, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons.

The Elegant Spindle Assembly Checkpoint

Without this exquisitely engineered system, the cell risks distributing an uneven number of chromosomes to the daughter cells. Read More ›
kendall-ruth-8CTz62aHidw-unsplash
Photo credit: Kendall Ruth on Unsplash.

Herding Chromosomes in the Mitosis Corral

The molecules of life do much more than convey information. They combine and impose physical forces on each other in intricate, functional ways. Read More ›

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