This review furthers the argument that I have developed elsewhere that the eukaryotic cell division cycle is elegantly engineered and irreducibly complex. Read More ›
Even a single unattached kinetochore is sufficient to trigger the wait anaphase signal, which inhibits activation of the APC/C that drives entry into anaphase. Read More ›
A crucial aspect of mitosis is the movement of chromosomes — initially the alignment of as paired sister chromatids during prometaphase and metaphase. Read More ›