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junk DNA

“Junk” DNA Discovered to Have Both Cellular and Microevolutionary Functions

Evolutionists have long sought mechanisms for the origin of reproductive barriers between populations, mechanisms which are thought to be key to the formation of new species. A recent article in ScienceDaily finds that “Junk DNA” might be the “mechanism that prevents two species from reproducing.” Basically, so-called “junk”-DNA is involved in helping to package chromosomes in the cell. If two species have different “junk” DNA, then this prevents the proteins in the egg from properly packaging the chromosomes donated by the sperm. The organism does not develop properly. As the article, titled “Junk DNA Mechanism That Prevents Two Species From Reproducing Discovered,” explains: during early development, the proteins required for cell division come from the mother. The researchers speculate that Read More ›

Experimental Data Force Researchers to Admit There’s “No Such Thing As Junk RNA”

Originally, proponents of neo-Darwinian evolution lauded “junk” DNA as functionless genetic garbage that showed life is the result of blind and random mutational events. Then “junk” DNA was disproved by the discovery that the vast majority of DNA is being transcribed into RNA. Did the failure of this Darwinian assumption cause evolutionists to terminate their love affair with biological “junk”? Of course not. They just shifted their argument back, claiming that the cell is full of “junk RNA”–DNA that is being transcribed into RNA but still does nothing in the cell. Earlier this year we reported on a Nature paper suggesting function for “junk” RNA. Now a Science Daily NewsArticle is confirming that finding. Aptly titled “No Such Thing As Read More ›

Ken Miller Confuses Weak Assertions of Common Ancestry With Darwinian Evolution of Blood Clotting Cascade (Updated)

Update 8/7/13: Since this response to Ken Miller was posted, even stronger evidence of function for the beta-globin pseudogene has been reported in the scientific literature, further refuting Miller’s argument. See Dover Revisited: With Beta-Globin Pseudogene Now Found to Be Functional, an Icon of the “Junk DNA” Argument Bites the Dust. In his book Only a Theory, one of Dr. Kenneth Miller’s main response to Michael Behe’s arguments for the irreducible complexity of the blood clotting cascade is that sequence similarities between various blood clotting factors demonstrates that they share a common ancestry. Indeed, in his response to me on the irreducible complexity of the blood clotting cascade, Miller again conflates evidence for common ancestry with evidence for Darwinian evolution. Read More ›

How The Junk DNA Hypothesis Has Changed Since 1980

As someone who has studied the concept of “junk DNA” for over twenty years, I am dismayed by two statements that appear repeatedly on various blog sites discussing evolution. No, I am not referring to arguments of the form “the onion has six times more DNA than do mammals; therefore, there is no deity,” that are invariably followed by terms of disparagement hurled at anyone who even marginally departs from the Darwinian perspective. Rather, my consternation stems from a half-truth and a false fact that are recycled ad nauseum by those who apparently believe that, despite all the genomic and transcriptomic data that have been obtained only in this decade — data that have overturned a number of trenchant assumptions–a certain hypothesis published in 1980 is outside the purview of serious questioning.

The half-truth is the oft-read comment that goes something like this: “No one ever asserted that junk DNA is without function…it was long suspected that these sequences have important roles in the cells.” Now, to be fair, it is correct to say that models for, say, repetitive DNA-based operations in metazoan development, have been proposed since the 1960s.1 It is also true that the evolutionary process of exaptation — the accidental acquisition of a function — has been used to explain how the odd transposon here or there along a chromosome can regulate a locus. Nonspecific effects of “extra” DNA on the cell have also been suggested for around three decades, if not longer. That said, the junk DNA hypothesis that one commonly reads as being an unassailable observation, as an incontrovertible empirical conclusion, presents as a clear prediction that the vast majority of non-gene sequences are devoid of any precise specificational role in ontogeny. Allow me to explain.

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Francis Collins, Karl Giberson, and Books and Culture Promote Misconceptions About Intelligent Design, Falsifiability & Junk DNA

In the media, it’s not unusual for an interviewer and interviewee to hold similar views on whatever subject they are discussing. Radio show hosts and podcasters, for example, commonly interview friendly guests. But imagine if Paul Allen interviewed Bill Gates on the merits of Microsoft, and then published the interview as an independent journalistic article in Wired magazine. Not only would it would read like a paid advertisement, but critics would begin wondering if Wired was in business to promote Microsoft products. The Microsoft example is of course fictional, but something like it happened recently when Karl Giberson (executive vice president of the BioLogos Foundation) interviewed Francis Collins (the president of BioLogos), and then published the interview in Christianity Today‘s Read More ›

God and Evolution: A Response to Stephen Barr (part 3)

This is the final installment of three posts responding to Stephen Barr. The first post can be found here, and the second post can be found here.

The Collins/Barr Approach: A God Who Misleads?

Stephen Barr identifies himself with the position of Francis Collins who argues that although evolution looks like “a random and undirected process,” it nevertheless could have been guided by God. “Evolution could appear to us to be driven by chance, but from God’s perspective the outcome would be entirely specified.” [Collins, The Language of God, p. 205.]

Barr takes me to task for highlighting Collins’ use of the word “could” because I implied that “Collins is not sure whether God did in fact know beforehand. Anyone who has read Collins’s book, however, should realize that Collins absolutely and unequivocally holds the belief that God knows all events from all eternity.” Really? In the same book that Collins says that God “could” have known and specified the outcome of evolution, he also claims that much of our DNA is basically junk that certainly was not the product of God’s intentional design. In particular, Collins goes on at length about “Ancient Repetitive Elements,” which he disparages as “genetic flotsam and jetsam” that make up “roughly 45 percent of the human genome.” Collins concedes that “some might argue that these are actually functional elements placed there by the Creator for a good reason, and our discounting of them as ‘junk DNA’ just betrays our current level of ignorance. And indeed, some small fraction of them may play important regulatory roles. But certain examples severely strain the credulity of that explanation.” [Language of God, p. 156, emphasis added] In other words, Collins rejects as credulous the idea that such DNA were planned by God for a reason. So much for the idea that God knew and specified the outcomes of evolution from eternity.

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Junk DNA RoundUp (and Rebuttal): How Neo-Darwinism Creates Junk-Hypotheses, Then Resists Their Demise

Sometimes after explaining how the now-defunct junk-DNA mindset was encouraged and fostered by neo-Darwinian evolution, evolutionists respond by asserting that nonetheless some individuals from their camp explored function for junk-DNA. This, they claim, absolves their neo-Darwinian camp from any charges of science-stopping, and shows that the neo-Darwinian paradigm did not hinder research into junk-DNA. But if a 2003 article in Science is any indication, then it seems that the neo-Darwinian paradigm did indeed impose a taboo on research into function for junk-DNA. As the article stated: Although catchy, the term ‘junk DNA’ for many years repelled mainstream researchers from studying noncoding DNA. Who, except a small number of genomic clochards, would like to dig through genomic garbage? However, in science Read More ›

“Junk” DNA: Darwinism’s Last Stand?

We are often told that the evidence for evolution is “overwhelming.” If “evolution” is defined as “change over time” or “minor changes within existing species,” this is a truism. But what if “evolution” means Charles Darwin’s theory? According to Darwin, all living things are descendants of a common ancestor that have been modified by unguided processes such as random variation and natural selection. Despite the hype from Darwin’s followers, the evidence for his theory is underwhelming, at best. Natural selection–like artificial selection–can produce minor changes within existing species. But in the 150 years since the publication of Darwin’s Origin of Species by Means of Natural Selection, no one has ever observed the origin of a new species by natural selection–much Read More ›

chromosome-structure-with-glowing-telomere-ends-in-scientifi-1464111025-stockpack-adobestock
Chromosome structure with glowing telomere ends in scientific 3D illustration, showing genetic material and cellular biology in dark blue background
Image Credit: INT888 - Adobe Stock

Guy Walks Into a Bar and Thinks He’s a Chimpanzee: The Unbearable Lightness of Chimp-Human Genome Similarity

I am often struck by how the topic of evolution in general, and chimp/human ancestry in particular, can be an immediate conversation opener that just as quickly becomes a conversation closer. Read More ›

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