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design logic

RNAPolymerase
Image: RNA polymerase, by Maria Voigt and PDB-101. This image is available under CC-BY-4.0 license. Attribution should be given to PDB-101 and Maria Voigt., CC BY 4.0 <https://creativecommons.org/licenses/by/4.0>, via Wikimedia Commons.

Recurring Design Logic in Attenuation Mechanisms

Despite the striking parallels between these systems in terms of the design logic, these attenuation systems are not evolutionarily related to one another. Read More ›
Embryo_in_flower
Photo credit: AudeNommick, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons.

Why Cell Division Challenges Darwinism

The eukaryotic cell cycle is just one of the many biological systems and processes that could not have arisen by numerous, successive, slight modifications. Read More ›
Aliivibrio-fischeri
Photo: Aliivibrio fischeri, by nicholas, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons.

Recurring Design Logic in Gene Regulation

A feature of biology that has struck me over the years is the phenomenon of recurring design logic, across systems that do not appear to be related by descent. Read More ›
bacteria
Photo credit: NIAID, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons.

Peer-Reviewed Paper Applies Systems Engineering to Bacterial Chemotaxis

The article further demonstrates how only a design-based framework yields significant insight into the higher-level organization of biological systems. Read More ›
cave fish
Photo: Cavefish (Phreatichthys andruzzii), by Hectonichus, CC BY-SA 3.0 <https://creativecommons.org/licenses/by-sa/3.0>, via Wikimedia Commons.

Brian Miller: “The Unreasonable Effectiveness of Engineering in the Biological Sciences”

Dr. Miller takes on a number of specific examples including the celebrated eyeless cavefish, which he “used to think was an absolute win for microevolution.” Read More ›
Area 51
Photo: Area 51, by X51 (Flickr: https://www.flickr.com/photos/x51/ Web: http://x51.org/), CC BY-SA 3.0 <http://creativecommons.org/licenses/by-sa/3.0/>, via Wikimedia Commons.

Biology as Reverse Engineering

An analogy I like to use is NASA finding a crashed spaceship in a cave located in Area 51. Read More ›
flagellum
irreducible complexity
Image: Bacterial flagellar motor, from Unlocking the Mystery of Life, Illustra Media.

Bacterial Flagellum Demonstrates the Explanatory and Predictive Power of Engineering Models

Dean Schulz investigated the design of the flagellum with a method that could be described as groundbreaking. Read More ›
Coris_gaimard_real
Photo: A labrid fish, by laszlo-photo, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons.

Studies on Labrid Fish Confirm Operational Gravity Well Model for Adaptation

The extent to which the authors recognize the implications of their conclusions is difficult to say. Read More ›
Galápagos finch
Photo: Galápagos finch, by kuhnmi, via Flickr.

Engineering Better Explains Adaptation than Evolutionary Theory

The genetic variation in any species is confined to a limited set of variables such as a finch beak’s thickness. Read More ›
fish
Photo credit: David Clode via Unsplash.

How Engineers Helped Save Biology from Evolutionary Theory

Design motifs such as four-bar linkages and control systems must meet exacting requirements whether implemented in a space shuttle or a fish. Read More ›

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