Tag: spindle assembly checkpoint

^{Type
post

Author
Jonathan McLatchie

Date
May 26, 2025

Categories
Evolution
Intelligent Design
Medicine
Tagged
, anaphase, aneuploidy, biology, biologyu, cancer, cancer cells, cell fusion, cell proliferation, cells, chromatids, chromosomal instability, chromosome, chromosome missegregation, cohesin ring, cytokinesis failure, DNA, E-Cadherin, endoreduplication, eukaryotic cell cycle, intelligent cause, intelligent design, Irreducible Complexity, kinetochore, micronuclei, mitotic cell division, mitotic spindle, oocytes, proteasome, securin, separase, spindle assembly checkpoint, tetraploidization, tetraploidy, tumorigenesis, tumors}

How Do Mitotic Errors Affect Cell Proliferation?

_{Jonathan McLatchie
May 26, 2025

Evolution, Intelligent Design, Medicine

12}

This review furthers the argument that I have developed elsewhere that the eukaryotic cell division cycle is elegantly engineered and irreducibly complex. Read More ›

^{Type
post

Author
Andrew McDiarmid

Date
January 23, 2025

Categories
Engineering
Evolution
Intelligent Design
Tagged
, cell division, cellular life, Charles Darwin, checkpoints, effectors, foresight, ID the Future, intelligent design, Irreducible Complexity, Jonathan McLatchie, podcast, self-replication, sensors, spindle assembly checkpoint}

Engineered Elegance: Checkpoint Pathways of the Cell Cycle

_{Andrew McDiarmid
January 23, 2025

Engineering, Evolution, Intelligent Design

2}

One of the most incredible features of cellular life is the capability of self-replication. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
August 27, 2024

Categories
Intelligent Design
Medicine
Tagged
, anaphase, cancer, chromosomes, Down syndrome, kinetochores, metaphase, microtubules, mitotic spindle, phosphatase, prometaphase, spindle assembly checkpoint, tumors, yeast}

Engineered Elegance: Generating the Wait Anaphase Signal

_{Jonathan McLatchie
August 27, 2024

Intelligent Design, Medicine

10}

Even a single unattached kinetochore is sufficient to trigger the wait anaphase signal, which inhibits activation of the APC/C that drives entry into anaphase. Read More ›

^{Type
post

Author
Jonathan McLatchie

Date
August 26, 2024

Categories
Intelligent Design
Life Sciences
Tagged
, anaphase, cell division, chromatids, chromosomes, Down syndrome, eukaryotic cell cycle, kinetochore, microtubules, mitosis, mitotic cell division, prometaphase, prophase, proteins, quality control, somatic cells, spindle assembly checkpoint, telophase}

The Elegant Spindle Assembly Checkpoint

_{Jonathan McLatchie
August 26, 2024

Intelligent Design, Life Sciences

11}

Without this exquisitely engineered system, the cell risks distributing an uneven number of chromosomes to the daughter cells. Read More ›