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The First Rule of Adaptive Evolution: A reply to Jerry Coyne

At his blog, Why Evolution is True, Jerry Coyne, professor of evolutionary biology at the University of Chicago, has been analyzing my recent paper, “Experimental Evolution, Loss-of-Function Mutations, and ‘The First Rule of Adaptive Evolution,’” which appears in the latest issue of the Quarterly Review of Biology. Although I usually don’t respond to blog posts I will this time, both because Coyne is an eminent scientist and because he does say at least one nice thing about the paper.

First, the nice thing. About half-way through his comments Professor Coyne writes:

My overall conclusion: Behe has provided a useful survey of mutations that cause adaptation in short-term lab experiments on microbes (note that at least one of these–Rich Lenski’s study– extends over several decades).

Thanks. Much appreciated.

Next, he turns to damage control. Directly after the mild compliment, Coyne registers his main complaint about the paper: the conclusions supposedly can only be applied to laboratory evolution experiments and say little about (Darwinian) evolution in nature. “But his conclusions may be misleading when you extend them to bacterial or viral evolution in nature, and are certainly misleading if you extend them to eukaryotes (organisms with complex cells), for several reasons.” Below I deal with Coyne’s three reasons in turn.

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Martin Gaskell and the Argument From Scientific “Consensus”

One needs to hammer and hammer away at the simple but crucial lesson of the scandalous Martin Gaskell case out of the University of Kentucky. A superbly qualified astronomer was rejected for a job because he expressed very modest Darwin doubts. Darwinists and their useful idiots are full of reminders to us to recall that a “consensus” of scientists compels our assent to Darwinian evolution. Yet with the Gaskell story being merely the latest instance, we see again and again how Darwin-doubting scientists are punished for speaking up in even the mildest way. A fortune in research money is at stake, as well as institutional reputations. Anyone who’s had the experience of being penalized by an employer for saying something Read More ›

Darwinists in a Muddle: Do Lenski’s Microbes Show “Why Evolution Is True,” or Not?

Jerry Coyne is ticked off that readers are attributing significance in the wider evolution debate to Michael Behe’s current paper in the Quarterly Review of Biology, explicating the results of viral and bacterial evolution studies — notably the famous long-term study of Richard Lenski: As I predicted, the IDers completely ignore the limitations of this paper (see my analyses here and here), and assert, wrongly, that Behe has made a powerful statement about evolution in nature. What Coyne “completely ignores” is that Darwinists have accustomed themselves to waving Lenski as a banner that makes “a powerful statement about evolution in nature.” In The Greatest Show on Earth, Richard Dawkins devoted an ecstatic and detailed discussion to Lenski’s work, enthusing: Creationists Read More ›

Methinks New PNAS Paper Is Like a Weasel

A paper by Wilf and Ewens recently published online in the Proceedings of the National Academy of Sciences, titled “There’s plenty of time for evolution,” reads like a printed version of Groundhog Day — the classic movie where comedian Bill Murray keeps awakening to find it’s the same day again. The paper’s authors sniff at unnamed benighted folks who think there hasn’t been enough time for (Darwinian) evolution to build the complexity we see in life. Not so, they protest. Why, all one has to do to see the light is to use the right mathematical model: “After guessing each of the letters, we are told which (if any) of the guessed letters are correct, and then those letters are Read More ›

Prehistoric “Man” as a Case of Epistemological Regress: Some Historical Lessons From Lukacs and Koestler

Consider this from John Lukacs At the End of An Age (2002):

In Chapter 1 of this book I suggested another fundamental limitation of Darwinism, which is the application of Evolution ever further and further backward, claiming that humans may have existed as early as one million years ago. That is a prime example of how unreason lies buried at the bottom of any and every materialist interpretation of mankind, because of its thesis of matter preceding human mind, with mind gradually appearing: when? perhaps in dribs and drabs, much later. (I happen to believe that there is no such thing as ‘pre-historic’ man, historicity being the fourth dimension of human existence from the beginning.) But perhaps the essential fault of Darwinism is its implicit denial that there is any fundamental difference, no matter how physically slight, between human beings and all other living beings. One need not be a religious believer to struggle against this notion: for if there is really no essential difference between human beings and all other living creatures, then there is no reason to have laws and institutions and mores prohibiting certain human acts and protecting human dignity, indeed, human lives. (pp. 120-121)

Lukacs, of course, is saying that Darwinists completely misconstrue humanness, both in the context of what it means to be human in time (historicity) and in the unique qualities of what humanness is (the mind). Because Darwinists are infatuated with morphological affinities, ape-like “ancestors” become “prehistoric man.” But (whatever else we may say of primordial hominid forms millions of years ago), is this “man”? Without the unique attributes of empathy, love, reasoning, a sense of the numinous, etc., can there be a “man” before there is a history of mankind? It seems doubtful. In short, is “prehistoric man” an oxymoron? Lukacs is correct in suggesting that it is. At best, the alternative is to see the grunts and groans of ape-like creatures as a largely seamless continuum to Plato’s dialogues, Aristotle’s Nicomachean Ethics, and onward. Darwin tried to make his case for it and it has been problematic ever since, sometimes with tragic consequences.

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Icons of Evolution 10th Anniversary: Paul Nelson

Display content from YouTube Click here to display content from YouTube. Learn more in YouTube’s privacy policy. Always display content from YouTube Open video directly At 4:38 of this interview, Paul Nelson says that the Miller-Urey experiment is incorrectly interpreted by textbooks as having “synthesized life.” What he meant to say was “the building blocks of life.” Dr. Nelson regrets the error.

Craig Venter’s Artificial Life: A Milestone in Overestimation

Living in two minds has gotta be tough. Perhaps that’s why the notable and irascible Craig Venter has made such a career out of bucking the system.

“I have almost no visual memory; I think almost entirely in concepts,” says Venter, explaining his mental peculiarities.

The pioneering biochemist won national headlines earlier this year by announcing that he and a team of privately-funded fellow researchers had produced “artificial life.” The truth, however, is more modest — what they succeeded in doing was determining the DNA coding sequence of one of the simplest bacteria they could find, minutely altering it, then artificially reconstructing this sequence of DNA from subunits supplied in chemical solution, removing the DNA from a bacterial cell, then re-inserting this new DNA “software” into the dormant cellular machinery. From there, the bacterial cell successfully read the inserted instructions, and transformed into the desired organism.

Anyone who’s ever used a flash drive in a computer will see the analogy — without the working interface software and hardware of the computer itself, the information stored in the drive is inert and useless. While certainly deserving of note, Venter’s achievement hardly negates the need for the pre-existing complexity of a functioning cell.

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Michael Behe’s New Paper in Quarterly Review of Biology Now Available for Free Download

For those of you wondering if you might be able to get your hands on Michael Behe’s latest paper (which we’ve been covering here at ENV), I have good news. “Experimental Evolution, Loss-of-Function Mutations, and ‘The First Rule of Adaptive Evolution,’” is now available as a free PDF at Behe’s Lehigh University website.

Michael Behe’s Challenge: A Conversation with Biologist Ann Gauger

At Why Evolution Is True, Jerry Coyne pictures a newly rediscovered and rather unhandsome fly native to a particular rock in Kenya (and nowhere else) where it sports about in the bat guano deposited in a cleft in the rock. The fly has only vestigial wings — “evidence for evolution, of course,” notes Dr. Coyne. Isn’t it interesting how “evidence for evolution” tends to be, as in this example, evidence not for the building up of new functionality but for its loss, where the loss has some adaptive advantage? Losing information is one thing — like accidentally erasing a computer file (say, an embarrassing diplomatic cable) where, it turns out in retrospect, you’re better off now that’s it not there anymore. Gaining information, building it up slowly from nothing, is quite another and more impressive feat. Yet it’s not the loss of function, and the required underlying information, but its gain that Darwinian evolution is primarily challenged to account for.

That’s the paradox highlighted in Michael Behe’s new review essay in Quarterly Review of Biology (“Experimental Evolution, Loss-of-Function Mutations, and “The First Rule of Adaptive Evolution“). It’s one of those peer-reviewed, Darwin-doubting biology journal essays that, as we’re confidently assured by the likes of the aforesaid Jerry Coyne, don’t actually exist. Casey Luskin has been doing an excellent job in this space of detailing Michael Behe’s conclusions. Reviewing the expansive literature dealing with investigations of viral and bacterial evolution, Dr. Behe shows that adaptive instances of the “diminishment or elimination” of Functional Coding ElemenTs (FCTs) in the genome overwhelmingly outnumber “gain-of-FCT events.” Seemingly, under Darwinian assumptions, even as functionality is being painstakingly built up that’s of use to an organism in promoting survival, the same creature should, much faster, be impoverished of function to the point of being driven out of existence. Jerry Coyne’s Kenyan fly may then be the opposite of “evidence for evolution” of the kind that Darwinists really need.

So far the masters of evolutionary apologetics have ignored Behe’s damaging article. [Update: Coyne has now done so. More anon.] Trying to imagine what they would or will say if they can ever carve out the time from a busy schedule to read it, I posed a few questions to Dr. Ann Gauger, developmental biologist and senior research scientist at Biologic Institute.

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