It is extremely difficult to envision how an ordered (and tightly regulated) cascade or pathway, such as complement, could have arisen in step-wise Darwinian manner.
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We are well acquainted by now with the most fashionable neo-Darwinian model for the origin of novel biological information: gene duplication and divergence.
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It wasn't long ago that Laurence Moran and PZ Myers were telling us that the genome is not even pervasively transcribed and that this amounted to evidence that the majority of our DNA is junk.
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In tribute to this masterpiece of design, I have just published a detailed literature review in which I describe the processes underlying its self-assembly and operations.
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