The success of science rests on forgetfulness, i.e. a group of people agrees to shelve the discussion of the basis of things and work on something else.
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Mary Shelley said she got the idea for Frankenstein from experiments by Charles Darwin's grandfather Erasmus, giving life to a piece of spaghetti.
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A far more effective materialist response to fine-tuning is the "Copernican" Principle (though Copernicus would have rejected it), sometimes called the Principle of Mediocrity.
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