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Brian Miller: Rarity and Isolation of Proteins in Sequence Space

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Evolution
Intelligent Design
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Was the universe designed to evolve through natural processes? In a recent book, theologian Rope Kojonen has argued that evolutionary mechanisms work in harmony with intelligent design to produce the diversity of life we see on Earth. But can these fundamentally different processes really work together? On a new episode of ID the Future, host Casey Luskin speaks with physicist Dr. Brian Miller to explore why Kojonen’s theory fails on scientific grounds.

In this episode, Dr. Miller delves into the rarity and isolation of proteins in sequence space. Kojonen takes mainstream evolutionary mechanisms for granted, positing that the laws of nature are specially designed to allow every protein in nature to evolve through standard natural processes. But Miller shows that the limits of protein evolution are very real and very problematic for Kojonen’s model. He explains in detail multiple lines of evidence that show how unlikely it is that protein sequences occur naturally or by chance in sequence space. Miller reports on research showing that the probability of a protein continuing to work after each mutation drops precipitously. He also explains that even the most similar proteins are about 80 percent different from each other. It all adds up to a headache for evolutionary theory, and the headache doesn’t go away when you marry mainstream evolutionary theory with intelligent design.

Download the podcast or listen to it here. This interview is part of a series hosted by Casey Luskin responding to Dr. Kojonen’s proposal. Listen to more episodes in the series below.

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Andrew McDiarmid

Director of Podcasting and Senior Fellow
Andrew McDiarmid is Director of Podcasting and a Senior Fellow at Discovery Institute. He is also a contributing writer to Mind Matters. He produces ID The Future, a podcast from the Center for Science & Culture that presents the case, research, and implications of intelligent design and explores the debate over evolution. He writes and speaks regularly on the impact of technology on human living. His work has appeared in numerous publications, including the New York Post, Houston Chronicle, The Daily Wire, San Francisco Chronicle, Real Clear Politics, Newsmax, The American Spectator, The Federalist, Technoskeptic Magazine, and elsewhere. In addition to his roles at Discovery Institute, he promotes his homeland as host of the Scottish culture and music podcast Simply Scottish. Andrew holds an MA in Teaching from Seattle Pacific University and a BA in English/Creative Writing from the University of Washington.
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