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Lab-Grown Lungs Transplanted into Pigs

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Bioethics
Medicine
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The human organ shortage is one of the great bioethical dilemmas of our time. Expanding the organ supply is a matter of life and death. But some proposed remedies — such as harvesting vital organs from the cognitively disabled as a form of euthanasia — are monstrous and would break every solemn promise made to the public about transplant medicine.

But there are ethical proposals too, such as making organs from one’s own stem cells. A big advance in this regard was recently achieved with pigs. From the Science News story:

For the first time, researchers have created lungs in the lab and successfully transplanted them into pigs.

These bioengineered lungs . . . developed healthy blood vessels that allowed pigs to live for several weeks after surgery without medical complications. That’s a significant improvement from previous efforts: Lab-grown lungs implanted in rodents failed within hours, before the lungs could develop the complex blood vessel network necessary for long-term survival.

If the new procedure can be adapted for humans, with bioengineered lungs grown from a patient’s own cells, that could reduce the risk of organ rejection and slash wait times for organ transplants. In the United States, where about 1,500 people currently are on a waiting list for a lung transplant, the average wait is a few months.

A Long Road Ahead

The same kind of research efforts are being made with kidneyshearts, and other organs. It’s still a long road ahead, but if this research proceeds to clinical practice, countless lives could be saved without compromising transplant ethics.

During the stem-cell controversy, President George W. Bush told us to never underestimate the imagination and skill of scientists. This experiment demonstrates his point precisely.

To which I would add, contrary to the lies of the animal-rights movement, never doubt the importance and efficacy of animal experiments in developing medicines and new life-saving techniques. This “grim good” research could not be accomplished on computers or cell lines. It requires living research subjects.

That leaves three choices: Sacrifice humans in the research; use pigs and other animals; or, don’t do the research.

The first choice would be unthinkable and the third would be derelict. I choose door No. 2.

Photo credit: Werbetrommlerin, via Pixabay.

Cross-posted at The Corner.

Wesley J. Smith

Chair and Senior Fellow, Center on Human Exceptionalism
Wesley J. Smith is Chair and Senior Fellow at Discovery Institute’s Center on Human Exceptionalism. Wesley is a contributor to National Review and is the author of 14 books, in recent years focusing on human dignity, liberty, and equality. Wesley has been recognized as one of America’s premier public intellectuals on bioethics by National Journal and has been honored by the Human Life Foundation as a “Great Defender of Life” for his work against suicide and euthanasia. Wesley’s most recent book is Culture of Death: The Age of “Do Harm” Medicine, a warning about the dangers to patients of the modern bioethics movement.
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